CD 8 Controls T Cell Cross - Reactivity Andrew

This information is current as CD 8 Controls T Cell Cross - Reactivity

Controls T Cell Expansion Subset of CD 1 d - Restricted αα CD 8 − CD 4 and Andrew

CD8 controls T cell cross-reactivity.

Estimates of human αβ TCR diversity suggest that there are <10(8) different Ag receptors in the naive T cell pool, a number that is dwarfed by the potential number of different antigenic peptide-MHC (pMHC) molecules that could be encountered. Consequently, an extremely high degree of cross-reactivity is essential for effective T cell immunity. Ag recognition by T cells is unique in that it invo...

Controls T Cell Cross - Reactivity Andrew

Controls T Cell Cross - Reactivity